size : | Price | Quantity | |
---|---|---|---|
1 mg | $35.00 | ||
5 mg | $100.00 |
17-DMAG (467214-20-6) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and induces apoptosis in a variety of tumor cell lines. Inhibits angiogenesis. Cell Permeable.
References/Citations:
1) Glaze et al. (2005), Preclinical toxicity of geldanamycin analog 17-(dimethylaminoethylamino)-demethoxygeldanamycin (17-DMAG) in rats and dogs; potential clinical relevance; Cancer Chemother. Pharmacol., 56 637
2) Kaur et al. (2004), Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator; Clin. Cancer Res., 10 4813
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17-DMAG (467214-20-6) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and induces apoptosis in a variety of tumor cell lines. Inhibits angiogenesis. Cell Permeable.
References/Citations:
1) Glaze et al. (2005), Preclinical toxicity of geldanamycin analog 17-(dimethylaminoethylamino)-demethoxygeldanamycin (17-DMAG) in rats and dogs; potential clinical relevance; Cancer Chemother. Pharmacol., 56 637
2) Kaur et al. (2004), Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator; Clin. Cancer Res., 10 4813
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