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2-NBD-Glucose | Glucose uptake probe

2-NBD-Glucose (186689-07-6) is a fluorescent glucose uptake probe. May be used to monitor glucose uptake in live cells and as a cell viability indicator.1,2 Has been used to measure glucose uptake in cultured hippocampal astrocytes using confocal epifluorescence microscopy.3 NBD fluorescence typically displays excitation/emission maxima of 465/540 nm. Cell permeable.

References/Citations
1) Yoshioka et al. (1996), A novel fluorescent derivative of glucose applicable to the assessment of glucose uptake activity of Escherichia coli; Biochim. Biophys. Acta, 1289 5
2) Yamada et al. (2000), Measurement of glucose uptake and intracellular calcium concentration in single, living, pancreatic beta-cells; J. Biol. Chem., 275 22278
3) Loaiza et al. (2003), Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy; J. Neurosci., 23 7337

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Focus Biomolecules supplier, chemical structure of 2-NBD-Glucose | Glucose uptake probe | CAS 186689-07-6

Catalog#  10-1459

$40.00
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CAS:
186689-07-6
Catalog Number:
10-1459
Activity:
Glucose uptake probe
Chemical Name:
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
Molecular Weight:
342.27
Molecular Formula:
C12H14N4O8
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Dark yellow to orange/red solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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