BOGO Promo: Stem Cell Small Molecules!

Small molecule cell signaling modulators can be used to induce each aspect of stem cell culture: Generation, Proliferation, Differentiation, etc. These biochemicals can also be combined into stem cell culture cocktails (e.g. CEPT). Focus Biomolecules is your go-to source for stem cell culture reagents, and through December 31, 2026, many are Buy One Get One Free!

**Use promo code SCbogo2026 when placing your order for applicable products.

Find your stem cell culture small molecules in these categories (or just do a search):

Dedifferentiation

  • Trichostatin A | HDAC inhibitor
    CAS:
    58880-19-6
    Catalog Number:
    10-2110
    Activity:
    HDAC inhibitor
    Alternate Names:
    TSA
    Chemical Name:
    (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
    Molecular Weight:
    302.38
    Molecular Formula:
    C17H22N2O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Verteporfin | YAP Inhibitor
    CAS:
    129497-78-5
    Catalog Number:
    10-3487
    Activity:
    YAP inhibitor
    Chemical Names:
    (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
    Alternate Name:
    CL 318,952; BPD-MA
    Molecular Weight:
    718.79
    Molecular Formula:
    C41H42N4O8
    Solubility:
    Soluble in DMSO (up to 14 mg/ml)
    Physical Properties:
    Black solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Purmorphamine | Smoothened activator
    CAS:
    483367-10-8
    Catalog Number:
    10-4622
    Activity:
    Smoothened activator
    Chemical Name:
    1-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
    Molecular Weight:
    520.62
    Molecular Formula:
    C31H32N6O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • RepSox | TGFß type I / ALK5 inhibitor
    CAS:
    446859-33-2
    Catalog Number:
    10-4546
    Activity:
    TGFß type I/ALK5 inhibitor
    Chemical Names:
    2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; E-616452; SNJ 2511
    Molecular Weight:
    287.32
    Molecular Formula:
    C17H13N5
    Solubility:
    Soluble in DMSO (>25 mg/ml); ethanol (10 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • SMER28 | Autophagy inducer
    CAS:
    307538-42-7
    Catalog Number:
    10-1287
    Activity:
    Autophagy inducer
    Chemical Name:
    6-Bromo-4-allylaminoquinazoline
    Molecular Weight:
    264.12
    Molecular Formula:
    C11H10BrN3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 2 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Dedifferentiation Products

Differentiation

View All Differentiation Products

Generation / Reprogramming

  • OAC2 | Enhances stem cell reprogramming
    CAS:
    6019-39-2
    Catalog Number:
    10-3203
  • Senexin B | CDK8/19 inhibitor
    CAS:
    1449228-40-3
    Catalog Number:
    10-4863
  • WS6 | Stimulates pancreatic ß-cell proliferation
    CAS:
    1421227-53-3
    Catalog Number:
    10-5666
  • Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant
    CAS:
    1273579-40-0
    Catalog Number:
    10-4912
    Activity:
    ROCK II inhibitor / Stem cell cytoprotectant
    Chemical Names:
    (3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide
    Molecular Weight:
    436.51
    Molecular Formula:
    C24H28N4O4
    Solubility:
    Soluble in DMSO (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • GSK126 | EZH2 methyltransferase inhibitor
    CAS:
    1346574-57-9
    Catalog Number:
    10-3394
    Activity:
    EZH2 methyltransferase inhibitor
    Chemical Names:
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
    Molecular Weight:
    526.69
    Molecular Formula:
    C31H38N6O2
    Solubility:
    Soluble in DMSO (16 mg/ml)
    Physical Properties:
    Cream solid
    Purity:
    >98% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Generation / Reprogramming Products

Hippo Pathway

View All Hippo Pathway Products

Proliferation

View All Proliferation Products

Self renewal/maintenance

  • Pyrintegrin | ß1-integrin agonist
    CAS:
    1228445-38-2
    Catalog Number:
    10-5468
  • TLX agonist 31 | TLX agonist
    CAS:
    3055146-41-0
    Catalog Number:
    10-3945
  • CPI203 | BET bromodomain inhibitor
    CAS:
    1446144-04-2
    Catalog Number:
    10-4048
  • Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant
    CAS:
    1273579-40-0
    Catalog Number:
    10-4912
    Activity:
    ROCK II inhibitor / Stem cell cytoprotectant
    Chemical Names:
    (3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide
    Molecular Weight:
    436.51
    Molecular Formula:
    C24H28N4O4
    Solubility:
    Soluble in DMSO (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Emricasan | pan-Caspase inhibitor
    CAS:
    254750-02-2
    Catalog Number:
    10-4280
    Activity:
    pan-Caspase inhibitor
    Chemical Names:
    (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid
    Alternate Name:
    IDN-6556; PF-03491390
    Molecular Weight:
    569.51
    Molecular Formula:
    C26H27F4N3O7
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Self renewal/maintenance Products

Other Stem cells

View All Other Stem cells Products

Wnt/ß-Catenin

  • IM-12 | GSK-3ß inhibitor
    CAS:
    1129669-05-1
    Catalog Number:
    10-5125
    Activity:
    GSK-3ß inhibitor
    Chemical Names:
    3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
    Molecular Weight:
    377.41
    Molecular Formula:
    C22H20FN3O2
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • IWR-1 endo | Wnt signaling inhibitor
    CAS:
    1127442-82-3
    Catalog Number:
    10-5081
    Activity:
    Wnt signaling inhibitor
    Molecular Weight:
    409.44
    Molecular Formula:
    C25H19N3O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white or yellow solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Wnt-C59 | Porcupine Inhibitor
    CAS:
    1243243-89-1
    Catalog Number:
    10-4605
    Activity:
    Porcupine Inhibitor
    Chemical Name:
    4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
    Molecular Weight:
    379.46
    Molecular Formula:
    C25H21N3O
    Solubility:
    Soluble in DMSO (up to 7 mg/ml) or in Ethanol (up to 6 mg/mL)
    Physical Properties:
    Tan solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • XAV-939 | Tankyrase inhibitor/Cardiomyogenesis inducer
    CAS:
    284028-89-3
    Catalog Number:
    10-1186
    Activity:
    Tankyrase inhibitor / Cardiomyogenesis inducer
    Chemical Name:
    2-[4-(Trifluoromethyl)phenyl]-7,8-dihydro-5H-thino[4,3-d]pyrimidin-4-ol
    Molecular Weight:
    312.31
    Molecular Formula:
    C14H11F3N2OS
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • KY-02111 | Wnt pathway inhibitor
    CAS:
    1118807-13-8
    Catalog Number:
    10-1437
    Activity:
    Wnt pathway inhibitor
    Chemical Name:
    N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
    Molecular Weight:
    376.86
    Molecular Formula:
    C18H17ClN2O3S
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Wnt/ß-Catenin Products

STEM CELL

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