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Product Details

3-Cyano-7-ethoxycoumarin | CYP450 fluorescent substrate

3-Cyano-7-ethoxycoumarin (11620-77-6) is a fluorescent substrate for cytochrome P450. Excitation/emission =  408/455 nm.1 May be used for CYP1A2 and CYP2C19 in intact cells.2 Cell permeable

References/Citations

1) White et al. (1988), A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin;  Anal. Biochem., 172 304
2) Donato et al. (2004), Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes;  Drug Metab. Dispos., 32 699

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3-Cyano-7-ethoxycoumarin | 11620-77-6 | Structure | Supplier

Catalog#  10-1440

$75.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
11620-77-6
Catalog Number:
10-1440
Activity:
CYP450 fluorescent substrate
Chemical Name:
7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
Molecular Weight:
215.20
Molecular Formula:
C12H9O3
Solubility:
Soluble in DMSO (up to 20 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)
Physical Properties:
Pale Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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