6,7-ADTN HBr | Dopamine receptor agonist
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $260.00 |
6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2 Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4
References/Citations:
- List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895
- Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629
- Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; J. Pharmacol. Exp. Ther., 268 417
- Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591
260.13
98% by TLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2 Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4
References/Citations:
- List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895
- Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629
- Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; J. Pharmacol. Exp. Ther., 268 417
- Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591
Related products
-
A-803467 | NaV1.8 blocker
From $50.00CAS:944261-79-4Catalog Number:10-1066Activity:NaV1.8 blockerChemical Name:5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamideMolecular Weight:357.8Molecular Formula:C19H16ClNO4Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Oxaprozin | NFkB inhibitor
From $40.00CAS:21256-18-8Catalog Number:10-1128Activity:NFκB inhibitorChemical Name:4,5-Diphenyl-2-oxazolepropanoic acidMolecular Weight:293.32Molecular Formula:C18H15NO3Solubility:Soluble in DMSOPhysical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
BCTC | TRPV1 blocker
From $60.00CAS:393514-24-4Catalog Number:10-1086Activity:TRPV1 blockerChemical Name:4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamideMolecular Weight:372.9Molecular Formula:C20H25ClN4OSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.