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8-Oxo-2'-deoxyguanosine | Marker for DNA damage

8-Oxo-2'-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes1. It is a critical biomarker for oxidative stress and carcinogenesis2,3.

References/Citations
1) Beckman et al. (1997), Oxidative decay of DNA; J. Biol. Chem., 272 19636
2) Andreoli et al. (2010), Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroquanosine, and their non-oxidized forms: daily concentration profile for healthy volunteers; Biomarkers, 15 221
3) Manini et al. (2009), Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers; Toxicol. Lett., 190 41

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Catalog#  10-2690

$38.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
88847-89-6
Catalog Number:
10-2690
Activity:
Marker for DNA damage
Alternate Names:
8-Oxo-dG; Oxo-dG
Chemical Name:
8-Oxo-7,8-dihydro-2'-deoxyguanosine
Molecular Weight:
283.25
Molecular Formula:
C10H13N5O5
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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