ALLM | Calpain inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $60.00 | ||
| 25 mg | $175.00 |
ALLM (136632-32-1) is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1 Weak inhibitor of the chymotrypsin-like activity of the proteasome.2 Cell permeable.
References/Citations:
1) Sasaki et al. (1990), Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins; J. Enzyme Inhib., 3 195
2) Vinitsky et al. (1992), Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex; Biochemistry, 31 9421
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
ALLM (136632-32-1) is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1 Weak inhibitor of the chymotrypsin-like activity of the proteasome.2 Cell permeable.
References/Citations:
1) Sasaki et al. (1990), Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins; J. Enzyme Inhib., 3 195
2) Vinitsky et al. (1992), Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex; Biochemistry, 31 9421
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1-855-FOCUS21
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