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Product Details

Anisomycin | Anoikis sensitizer

Anisomycin (22862-76-6) activates JNK/SAPKs and reduces c-fos and c-jun. Protein synthesis inhibitor. Anisomycin induces apoptosis and sensitizes cells to anoikis. Cell permeable.

References/Citations
1) Hazzalin et al. (1998), Anisomycin Selectively Desensitizes Signalling Components Involved in Stress Kinase Activation and fos and jun Induction; Mol. Cell. Bio., 8 1844
2) Mawji et al. (2007), A Chemical Screen Indentifies Anisomycin as an Anoikis Sensitizer That Functions by Decreasing FLIP Protein Synthesis; Cancer Res., 67 8307

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Catalog#  10-2056

$35.00
Quantity
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CAS:
22862-76-6
Catalog Number:
10-2056
Activity:
Anoikis sensitizer
Chemical Name:
(2R,3S,4S)-4-Hydroxy-2-)4-methoxybenzyl)pyrrolidin-3-yl acetate
Molecular Weight:
265.31
Molecular Formula:
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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