Apomorphine HCl | Dopamine agonist

CAS:
41372-20-7
Catalog Number:
10-1338
Activity:
Dopamine agonist
Chemical Name:
(R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinolone-10,11-diol hydrochloride
Alternate Names:
R-(-)-6aβ-aporphine-10,11-diol hydrochloride Hemihydrate
Molecular Weight:
312.78
Molecular Formula:
C17H17NO2• HCl 1/2H2O
Solubility:
Soluble in Water (up to 20 mg/ml)
Physical Properties:
Grey solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
100 mg$50.00
500 mg$150.00

Apomorphine (41372-20-7) is an archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo.1 Protects against MPTP-induced neurotoxicity in a mouse mode1,2 In clinical use for Parkinson’s disease.4,5

References/Citations:

1) Merck Index 14:746
2) Millan et al. (2002), Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes; J. Pharmacol. Exp. Therap., 303 791
3) Grunblatt et al. (1999), Apomorphine protects against MPTP-induced neurotoxicity in mice.; Mov. Discord, 14 612
4) Auffret et al. (2017), Apomorphine pump in advanced Parkinson’s disease: Effects on motor and nonmotor symptoms with brain metabolism correlations; J. Neurol. Sci, 372 279
5) Jenner and Katzenschlager (2016), Apomorphine – pharmacological properties and clinical trials in Parkinson’s disease; Parkinsonism. Related. Disord., 33 Suppl. 1:S13

CAS:
41372-20-7
Catalog Number:
10-1338
Activity:
Dopamine agonist
Chemical Name:
(R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinolone-10,11-diol hydrochloride
Alternate Names:
R-(-)-6aβ-aporphine-10,11-diol hydrochloride Hemihydrate
Molecular Weight:
312.78
Molecular Formula:
C17H17NO2• HCl 1/2H2O
Solubility:
Soluble in Water (up to 20 mg/ml)
Physical Properties:
Grey solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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