my account
Login
  Loading... Please wait...

Product Details

Aripiprazole | Dopamine receptor partial agonist

Aripiprazole (129722-2-9) is a clinically useful neuroleptic and antipsychotic agent.1 Dopamine D2 receptor antagonist and autoreceptor agonist.Improves symptoms of psychosis associated with Alzheimer's disease.3 Aripiprazole blocked cocaine-seeking behavior without affecting other rewarding behaviors in animal models.4

References/Citations
1) Green et al. (2004), Focus on aripiprazole; Curr. Med. Res. Opin., 20 207
2) Kikuchi et al. (1995), 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity; J. Pharmacol. Exp. Ther., 274 329
3) Madhusoodanan et al. (2008), Management of psychosis in patients with Alzheimer's isease: focus on aripiprazole; Clin. Interv. Aging, 3 491
4) Feltenstein et al. (2007), Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse; Biol. Psychiatry, 61 582

swipe
Focus Biomolecules supplier, chemical structure of Aripiprazole | Dopamine receptor partial agonist | CAS 129722-2-9

Catalog#  10-2314

$40.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
129722-12-9
Catalog Number:
10-2314
Activity:
Dopamine receptor partial agonist
Alternate Names:
OPC-14597
Chemical Name:
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Molecular Weight:
448.4
Molecular Formula:
C23H27Cl2N3O2
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the Aripiprazole | Dopamine receptor partial agonist to your wish list.