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Aspterric acid | Plant growth regulator

Aspterric acid (67309-95-9) is a fungal sequeterpenoid1 plant growth inhibitor discovered using a resistance-gene-directed approach.1 It is an inhibitor of dihydroxy-acid dehydratase (DHAD, IC50=0.31 and 0.5 μM for AteDHAD and AthDHAD respectively), an enzyme in the branched-chain amino acid biosynthetic pathway in plants and is an effective herbicide in spray applications. It has no significant cytotoxicity in human cell lines (up to 500 μM).2 Inhibits the development of pollen in Arabidopsis thalania.3

 

References/Citations

1) Tsuda et al. (1978), Aspterric acid, a new sesquiterpenoid of the carotene group, a metabolite from Aspergillus terreus IFO-6123. X-Ray crystal and molecular structure of its p-bromobenzoate; J. Chem. Soc. Chem. Commun., 4 161
2) Yan et al. (2018), Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action; Nature., 559 415
3) Shimada et al. (2002), Aspterric acid and 6-hydroxymellein, inhibitors of pollen development in Arabidopsis thaliana, produced by Aspergillus terreus; Z. Naturforsch. C., 57 459

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Catalog#  10-3498-0001

$100.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
67309-95-9
Catalog Number:
10-3498
Activity:
Plant growth regulator
Source:
Microbial product from Penicilium sp.
Molecular Weight:
266.33
Molecular Formula:
C15H22O4
Solubility:
Soluble in DMSO
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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