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Product Details

BAY K8644 | L-type calcium channel activator

BAY K8644 (71145-03-4) is an L-type Ca2+-channel activator with positive inotropic and vasoconstrictive effects.1-4

References/Citations
1) Schramm et al. (1983) Novel Dihydropyridines with positive inotropic action through activation of Ca2+ channels; Nature, 303 535
2) Yamamoto et al. (1984) Bay K8644 Differentiates bedtween potential and receptor operated Ca2+ channels; Eur. J. Pharmacol. 102 555
3) Thomas et al. (1985) A dihydropyridine (Bay K 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent; Circ. Res., 56 87
4) Shi et al. (2009) Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small molecule compounds; Cell Stem Cell, 3 568

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Catalog#  10-4518

$75.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
71145-03-4
Catalog Number:
10-4518
Activity:
L-type calcium channel activator
Chemical Name:
(±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate
Molecular Weight:
356.3
Molecular Formula:
C16H15F3N2O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
>98% by TLC
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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