GTPase

GTPases are enzymes that hydrolize GTP to GDP. They include elongation factors, G proteins (which interact with GPCRs, large GTPases, and tubulin. Some use accessory proteins to assist in their signaling functions.

  • Dynasore | Dynamin inhibitor

    CAS:
    304448-55-3
    Catalog Number:
    10-1427
    Activity:
    Dynamin inhibitor
    Chemical Name:
    3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
    Molecular Weight:
    322.32
    Molecular Formula:
    C18H14N2O4
    Solubility:
    Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 1 mg/ml).
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • MBQ-167 | Dual Rac/Cdc42 inhibitor

    CAS:
    2097938-73-1
    Catalog Number:
    10-4434
    Activity:
    Dual Rac/Cdc42 inhibitor
    Chemical Names:
    1-(9-Ethyl-9H-carbazol-3-yl)-5-phenyl-1H-1,2,3-triazole
    Molecular Weight:
    338.41
    Molecular Formula:
    C22H18N4
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
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  • MLS-532223 | GTPase inhibitor

    CAS:
    16616-39-0
    Catalog Number:
    10-1305
    Activity:
    GTPase inhibitor
    Chemical Name:
    1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
    Molecular Weight:
    251.24
    Molecular Formula:
    C15H9NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $62.00
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  • MLS-573151 | Cdc42 inhibitor

    CAS:
    10179-57-4
    Catalog Number:
    10-1193
    Activity:
    Cdc42 inhibitor
    Chemical Name:
    4-[3,5-Diphenyl-4,5-dihydropyrazol-1-yl]benzenesulfonamide
    Molecular Weight:
    377.47
    Molecular Formula:
    C21H19N3O2S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • MRTX849 | Covalent KRASG12C Inhibitor

    CAS:
    2326521-71-3
    Catalog Number:
    10-3928
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  • NSC23766 | Rac1 GTPase inhibitor

    CAS:
    733767-34-5
    Catalog Number:
    10-2731
    Activity:
    Rac1 GTPase inhibitor
    Chemical Names:
    N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
    Molecular Weight:
    530.98
    Molecular Formula:
    C24H35N7·3HCl
    Solubility:
    Soluble in DMSO (50 mg/ml); Water (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $67.00
    View Product This product has multiple variants. The options may be chosen on the product page
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