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Product Details

MLS-532223 | GTPase inhibitor

MLS-532223 is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.

References/Citations
1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10

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Focus Biomolecules cell signaling reagent supplier, chemical structure of MLS-532223 | GTPase inhibitor | CAS 16616-39-0

Catalog#  10-1305

$62.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
none available
Catalog Number:
10-1305
Activity:
GTPase inhibitor
Chemical Name:
1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular Weight:
251.24
Molecular Formula:
C15H9NO3
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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