BML-259 | CDK5/p25 inhibitor

CAS:
267654-00-2
Catalog Number:
10-1025
Activity:
CDK5/p25 inhibitor
Chemical Name:
N-(5-isopropyl-thiazol-2-yl)phenylacetamide
Molecular Weight:
260.36
Molecular Formula:
C14H16N2OS
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
white solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$60.00
25 mg$240.00
This product is also available in the following library:

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

References/Citations:

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

CAS:
267654-00-2
Catalog Number:
10-1025
Activity:
CDK5/p25 inhibitor
Chemical Name:
N-(5-isopropyl-thiazol-2-yl)phenylacetamide
Molecular Weight:
260.36
Molecular Formula:
C14H16N2OS
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
white solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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