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BML-278 | SIRT1 activator
BML-278 is a structurally novel activator of SIRT1 (EC50=1 μM). Displays selectivity over SIRT2 and 3 (EC50=25 and 50 μM respectively). Cell permeable.
References/Citations
1) Mai et al. (2009), Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors; J. Med.Chem.,52 5496
Catalog# 10-1063
$70.00
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CAS:
Not Available
Catalog Number:
10-1063
Activity:
SIRT1 activator
Chemical Name:
N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
Molecular Weight:
391.47
Molecular Formula:
C24H25NO4
Solubility:
Soluble in DMSO (up to 5 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
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