my account
Login
  Loading... Please wait...

Product Details

Bz-Val-Gly-Arg-AMC | Proteasome substrate

Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.

References/Citations
1) Gillardon et al. (2007), The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity; J. Neurochem., 101 1483
2) Kim et al. (2002), Navigation inside a protease: substrate selection and product exit in tricorn protease from Thermoplasma acidophilum; J. Mol. Biol., 324 1041
3) Dahlmann et al. (2000), Different proteasome subtypes in a single tissue exhibit different enzymatic properties; J. Mol. Biol., 303 643
4) Lightcap et al. (2000), Proteasome inhibition measurements: clinical application; Clin. Chem., 46 673

swipe
Image 1

Catalog#  10-2969

$30.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
87779-49-5
Catalog Number:
10-2969
Activity:
Proteasome substrate
Chemical Name:
Benzoyl-Val-Gly-Arg-(7-amido-4-methylcoumarin)
Molecular Weight:
705.7
Molecular Formula:
C30H37N7O6 CF3COOH
Solubility:
Soluble in DMSO.
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the Bz-Val-Gly-Arg-AMC | Proteasome substrate to your wish list.