Citalopram HBr | Serotonin uptake inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 50 mg | $52.00 | ||
| 250 mg | $208.00 |
Citalopram HBr (59729-32-7) is a potent and selective serotonin uptake inhibitor (SSRI) Ki=5.4 nM. Has no effect on norepinephrine or dopamine uptake.1 Displays cardioprotective effects in part by reducing expression of cytokine-induced endothelial adhesion molecules, ICAM-1 and VCAM-1.2 Clinically useful antidepressant.3 Attenuates ethanol intake.4
References/Citations:
1) Mateo et al. (2000), Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo; Neuropharmacology 39 2036
2) Lekakis et al. (2010), Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules; Int. J. Cardiol. 139 150
3) Cipriani et al. (2009), Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis; Lancet 373 746
4) Naranjo et al. (1987), The serotonin uptake inhibitor citalopram attenuates ethanol intake; Clin. Pharmacol. Ther. 41 266
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Citalopram HBr (59729-32-7) is a potent and selective serotonin uptake inhibitor (SSRI) Ki=5.4 nM. Has no effect on norepinephrine or dopamine uptake.1 Displays cardioprotective effects in part by reducing expression of cytokine-induced endothelial adhesion molecules, ICAM-1 and VCAM-1.2 Clinically useful antidepressant.3 Attenuates ethanol intake.4
References/Citations:
1) Mateo et al. (2000), Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo; Neuropharmacology 39 2036
2) Lekakis et al. (2010), Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules; Int. J. Cardiol. 139 150
3) Cipriani et al. (2009), Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis; Lancet 373 746
4) Naranjo et al. (1987), The serotonin uptake inhibitor citalopram attenuates ethanol intake; Clin. Pharmacol. Ther. 41 266
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