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Ciglitazone | PPAR gamma agonist

Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differentiation and angiogenesis. Cell permeable.

References/Citations
1) Cantello et al. (1994) [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents; J. Med. Chem. 37 3977
2) Xin et al. (1999) Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo; J. Biol. Chem. 274 9116

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Focus Biomolecules cell signaling reagent supplier, chemical structure of Ciglitazone | PPARγ agonist | CAS 74772-77-3

Catalog#  10-1047

$80.00
Quantity
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CAS:
74772-77-3
Catalog Number:
10-1047
Activity:
PPARγ agonist
Chemical Name:
(±)-5-[4-(1-Methylcyclohexylmethoxy)-benzyl]thiazolidine-2,4-dione
Molecular Weight:
333.45
Molecular Formula:
C18H23NO3S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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