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  • Focus Biomolecules reagent supplier, chemical structure of 8-pCPT-2-O-Me-cAMP-AM | Epac activator | CAS 1152197-23-3
    8-pCPT-2-O-Me-cAMP-AM (1152197-23-3) is a potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator.1 Induces RAP1 activation and insulin secretion in pancreatic beta cell lines...

  • Dibutyryl cAMP | Cell permeable cAMP
    Dibutyryl cAMP (16980-89-5) is a cell-permeable cAMP analog which mimics the effect of endogenous cAMP when applied to cells.1 Activates PKA.2,3 Induces morphological differentiation of astrocytes.4 Promotes differentiation...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of IBMX | PDE inhibitor | CAS 28822-58-4
    IBMX (28822-58-4) is a pan-specific inhibitor of phosphodiesterases (IC50=2-50 µM). Inhibition of PDEs leads to increased concentration of intracellular cAMP which activates PKA2. IBMX does not inhibit PDE8 or PDE93...

  • Focus Biomolecules cell signaling supplier, chemical structure ST-034307 | Adenylate cyclase 1 inhibitor | CAS 133406-29-8
    ST-034307 (133406-29-8) is a novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 μM . Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC11. It was also shown to inhibit AC1...