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Product Details

Cyclopamine | Inhibits hedgehog signaling

Cyclopamine (4449-51-8) is a naturally occurring steroidal alkaloid with teratogenic activity. Blocks sonic hedgehog signaling by binding to smoothened. Antitumor activity. Cell Permeable.

References/Citations
1) Watkins et al. (2003), Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer; Nature, 422 313

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Focus Biomolecules cell signaling reagent supplier, structure Cyclopamine | Inhibits hedgehog signaling | CAS 4449-51-8

Catalog#  10-1082

$45.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
4449-51-8
Catalog Number:
10-1082
Activity:
Inhibits hedgehog signaling
Molecular Weight:
411.63
Molecular Formula:
C27H41NO2
Solubility:
Soluble in DMSO (up to 4 mg/ml) or in Ethanol (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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