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Product Details

CYM-5541 | Allosteric sphingosine-1-phosphate receptor 3 agonist

CYM-5541 (945128-26-7) is a potent and selective allosteric agonist of the sphingosine-1-phosphate receptor 3 (S1P3; EC50’s = 72.3-132 nM).1,2

References/Citations
1) Guerrero et al. (2011), Probe Development Efforts for an Allosteric Agonist of Sphingosine 1-phosphate Receptor 3 (S1P3); Probe Reports from the NIH Molecular Libraries Program
2) Jo et al. (2012), Novel Selective Allosteric and Bitopic Ligands for the S1P3 Receptor; ACS Chem. Biol. 7 1975

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Catalog#  10-4493-0005

$50.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
945128-26-7
Catalog Number:
10-4493
Activity:
Allosteric sphingosine-1-phosphate receptor 3 agonist
Chemical Name:
N,N-Dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide
Alternate Name:
ML-249
Molecular Weight:
316.44
Molecular Formula:
C19H28N2O2
Solubility:
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20° (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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