Daptomycin (103060-53-3) is a cyclic anionic lipopeptide calcium-dependent antibiotic1. Useful for the treatment of serious Gram-positive infections including antibiotic-resistant strains such as MRSA and VRE2.
1) Jung et al. (2004), Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin; Chem. Biol., 11 949
2) Steenbergen et al. (2005), Dauptomycin: a lipopeptide antibiotic for the treatment of serious Gram-positive infections; J. Antimicrob. Chemother., 55 283