DC-Y13-27 | YTHDF2 inhibitor
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $50.00 | ||
| 25 mg | $165.00 |
DC-Y13-27 (3069691-93-6) is an inhibitor (IC50 = 21.8 µM) of the RNA N6-methyladenosine (m6A) reader YTHDF2.1 It significantly enhanced tumor growth inhibition in MC38 murine models in conjunction with radiotherapy and/or anti-PD-L1 therapy via an increase in the number of CD8+ T cells.
References/Citations:
- Wang et al. (2023), YTHDF2 inhibition potentiates radiotherapy anti-tumor efficacy; Cancer Cell 41 1294
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
DC-Y13-27 (3069691-93-6) is an inhibitor (IC50 = 21.8 µM) of the RNA N6-methyladenosine (m6A) reader YTHDF2.1 It significantly enhanced tumor growth inhibition in MC38 murine models in conjunction with radiotherapy and/or anti-PD-L1 therapy via an increase in the number of CD8+ T cells.
References/Citations:
- Wang et al. (2023), YTHDF2 inhibition potentiates radiotherapy anti-tumor efficacy; Cancer Cell 41 1294
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