Deferiprone | Iron Chelator

CAS:
30652-11-0
Catalog Number:
10-4950
Activity:
Iron chelator
Chemical Name:
3-Hydroxy-1,2-dimethylpyrid-4-one
Alternate Name:
Ferriprox
Molecular Weight:
139.15
Molecular Formula:
C7H9NO2
Solubility:
Soluble in Water (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
500 mg$20.00

Deferiprone (30652-11-0) is a clinically useful iron chelator.1 It attenuated blood-brain-barrier breakdown and brain mitochondrial dysfunction in rats with chronic iron-overload.2 Iron chelation therapy has been suggested as a possible therapy for Alzheimer’s Disease.3

References/Citations:

1) Hider and Hoffbrand (2018), The Role of Deferiprone in Iron Chelation; N. Engl. J. Med., 379 2140
2) Sripetchwandee et al. (2016), A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloid-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload., Neuroscience 332 191
3) Liu et al. (2018), Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications; Front. Neurosci, 12 632

CAS:
30652-11-0
Catalog Number:
10-4950
Activity:
Iron chelator
Chemical Name:
3-Hydroxy-1,2-dimethylpyrid-4-one
Alternate Name:
Ferriprox
Molecular Weight:
139.15
Molecular Formula:
C7H9NO2
Solubility:
Soluble in Water (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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