Size: | Price | Quantity | |
---|---|---|---|
500 mg | $20.00 |
Deferiprone (30652-11-0) is a clinically useful iron chelator.1 It attenuated blood-brain-barrier breakdown and brain mitochondrial dysfunction in rats with chronic iron-overload.2 Iron chelation therapy has been suggested as a possible therapy for Alzheimer’s Disease.3
References/Citations:
1) Hider and Hoffbrand (2018), The Role of Deferiprone in Iron Chelation; N. Engl. J. Med., 379 2140
2) Sripetchwandee et al. (2016), A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloid-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload., Neuroscience 332 191
3) Liu et al. (2018), Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications; Front. Neurosci, 12 632
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Deferiprone (30652-11-0) is a clinically useful iron chelator.1 It attenuated blood-brain-barrier breakdown and brain mitochondrial dysfunction in rats with chronic iron-overload.2 Iron chelation therapy has been suggested as a possible therapy for Alzheimer’s Disease.3
References/Citations:
1) Hider and Hoffbrand (2018), The Role of Deferiprone in Iron Chelation; N. Engl. J. Med., 379 2140
2) Sripetchwandee et al. (2016), A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloid-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload., Neuroscience 332 191
3) Liu et al. (2018), Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications; Front. Neurosci, 12 632
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