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Product Details

DMNQ | Induces ROS generation

DMNQ (6956-96-3) is a non-alkylating redox cycling quinone. A useful tool for studying reactive oxidant species and oxidative stress. Cellular effects are dependent on concentration and cell type.

References/Citations
1) Gant et al. (1988) Redox Cycling and Sulphydryl Arylation; Their Relative Importance in the Mechanism of Quinone Cytotoxicity to Isolated Hepatocytes; Chem. Biol. Interactions; 65 157
2) Stubberfield and Cohen (1989) Interconversion of NAD(H) to NADP(H). A cellular response to quinone-induced oxidative stress in isolated hepatocytes; Biochem. Pharmacol., 38 2631
3) Dypbukt et al (1994) Different prooxidant levels stimulate growth, trigger apoptosis or produce necreosis of insulin-secreting RINm5F cells. The role of intracellular polyamines; J. Biol. Chem., 269 30553
4) Henry and Wallace (1996) Differential mechanisms of cell killing by redox cycling and arylating quinones; Arch. Toxicol., 70 482

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Catalog#  10-4523

$65.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
6956-96-3
Catalog Number:
10-4523
Activity:
Induces ROS generation
Chemical Name:
2,3-Dimethoxy-1,4-naphthoquinone
Molecular Weight:
218.21
Molecular Formula:
C12H10O4
Solubility:
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
Yellow solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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