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Product Details

DMPO | Spin trap

DMPO (3317-61-1) is a hydrophilic spin trap for superoxide, O-, C-, S- and N-centered free radicals. DMPO is useful for both in vivo and in vitro studies. Cell Permeable.

1) Nishizawa et al. (2004), Hydroxyl radical generation caused by the reaction of singlet oxygen with the spin trap DMPO, increases significantly in the presence of biological reductants; Mol. Pharmacol., 6 597
2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59
3) Clement et al. (2005), Assignment of the EPR spectrum of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) superoxide spin adduct; J. Org. Chem., 70 1198
4) Gomez-Mejiba et al. (2009), Immuno-spin trapping of protein and DNA radicals: 'tagging' free radicals to locate and understand the redox process; Free Rad. Biol. Med., 42 530

Focus Biomolecules cell signaling reagent supplier, chemical structure of DMPO | Spin trap | CAS 3317-61-1

Catalog#  10-2299

Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
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Catalog Number:
Spin trap
Chemical Name:
5,5-Dimethyl-1-pyrroline N-oxide
Molecular Weight:
Molecular Formula:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Pale yellow oil or low melting point solid
99% by HPLC
99% by GC/MS
Storage Temperature:
Stable for 2 years as supplied. Protect from exposure to light and moisture. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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