DMPQ 2HCl | PDGFR inhibitor

CAS:
137206-97-4
Catalog Number:
10-1370
Activity:
PDGFR inhibitor
Chemical Name:
5,7-Dimethoxy-3-(4-pyridinyl)quinolone dihydrochloride
Molecular Weight:
339.22
Molecular Formula:
C16H14N2O2 2HCl
Solubility:
Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$65.00
25 mg$248.00

DMPQ 2HCl (137206-97-4) is a potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erB2, p56, PKA and PKC. Cell permeable.

References/Citations:

1) Dolle et al. (1994), Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′-monophosphate phosphodiesterase activity; J. Med. Chem., 37 2627

CAS:
137206-97-4
Catalog Number:
10-1370
Activity:
PDGFR inhibitor
Chemical Name:
5,7-Dimethoxy-3-(4-pyridinyl)quinolone dihydrochloride
Molecular Weight:
339.22
Molecular Formula:
C16H14N2O2 2HCl
Solubility:
Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee