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Product Details

DTG | High affinity sigma receptor agonist

DTG (97-39-2) is an agonist of the sigma (σ) receptor1 with roughly equal potency against both subtypes (σ1 and σ2 IC50’s ~ 30nM)2.

References/Citations

1) Weber et al. (1986), 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs; Proc. Natl. Acad. Sci. USA, 83 8784
2) Scherz et al. (1990), Synthesis and Structure-Activity Relationships of N,N’-Di-o-tolylguanidine Analogues, High-Affinity Ligands for the Haloperidol-Sensitive σ Receptor; J. Med. Chem., 33 2421

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Focus Biomolecules cell signaling supplier, chemical structure of DTG | High affinity sigma receptor agonist | CAS 97-39-2

Catalog#  10-4204-0100

$30.00
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CAS:
97-39-2
Catalog Number:
10-4204
Activity:
High affinity sigma receptor agonist
Chemical Name:
1,3-Di-o-tolylguanidine
Molecular Weight:
239.32
Molecular Formula:
C15H17N3
Solubility:
Soluble in DMSO (up to 10 mg/ml)
Physical Properties:
White solid
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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