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DU-14 | Sulfatase inhibitor

CAS:
186303-55-9
Catalog Number:
10-1187
Activity:
Sulfatase inhibitor
Chemical Name:
(p-O-Sulfamoyl)-N-tetradecanoyl tyramine
Molecular Weight:
426.62
Molecular Formula:
C22H38N2O4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

DU-14 (186303-55-9) inhibits steroid sulfatase (IC50=ca. 60 nM). Enhances learning and spatial memory in rats.1 Inhibits proliferation of human MCF-7 breast cancer cells.2

References/Citations:

1) Johnson et al. (2000), The effect of steroid sulfatase inhibition on learning and spatial memory; Brain Res., 865 286
2) Selcer et al. (1997), Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines; Cancer Res., 57 702

DU-14 | Sulfatase inhibitor is also available in the Cellular Metabolism Library.
CAS:
186303-55-9
Catalog Number:
10-1187
Activity:
Sulfatase inhibitor
Chemical Name:
(p-O-Sulfamoyl)-N-tetradecanoyl tyramine
Molecular Weight:
426.62
Molecular Formula:
C22H38N2O4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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