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Ebselen | Glutathione peroxidase mimic

Ebselen (60940-34-3) is a novel nontoxic selenium-containing multifunctional antioxidant and anti-inflammatory agent.1 Displays protective effects in reperfusion injury and stroke.2 Ebselen is an excellent scavenger of peroxynitrite.3 Acts as a glutathione peroxidase mimetic.4 Cell permeable.

References/Citations
1) Schewe et al. (1995), Molecular actions of ebselen - an anti-inflammatory antioxidant; Gen. Pharmacol., 26 1153
2) Parnham et al. (2000), Ebselen: prospective therapy for cerebral ischaemia; Expert. Opin. Investig. Drugs, 9 607
3) Masumoto et al. (1996), Kinetic study of the reaction of ebselen with peroxynitite; FEBS Lett., 398 179
4) Nakamura et al. (2002), Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis; J. Biol. Chem., 277 2687

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Focus Biomolecules supplier, chemical structure of Ebselen | Glutathione peroxidase mimic | CAS 60940-34-3

Catalog#  10-2288

$28.00
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CAS:
60940-34-3
Catalog Number:
10-2288
Activity:
Glutathione peroxidase mimic
Alternate Names:
PZ-51
Chemical Name:
2-Phenyl-1,2-benzisoselenazol-3(2H)-one
Molecular Weight:
274.18
Molecular Formula:
C13H9NOSe
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
Physical Properties:
Light yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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