Erucamide (112-84-5) is an endogenous fatty acid amide. It was able to ameliorate depression and anxiety-like behaviors in several mouse models. Significantly lowered levels of circulating adrenocorticotrophic hormone (ACTH) and corticosterone (CORT) suggesting a mechanism of action involving modulation of the hypothalamus-pituitary-adrenal axis.
1) Li et al. (2017), Antidepressant and anxiolytic-like behavioral effects of erucamide, a bioactive fatty acid amide, involving the hypothalamus-pituitary-adrenal axis in mice; Neurosci. Lett. 640 6