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Product Details

Etoposide | Topoisomerase II inhibitor

Etoposide (33419-42-0) is a chemotherapeutic agent that forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Etoposide blocks the cell cycle in S-phase and G2-phase.

References/Citations
1) Hande (1998) Etoposide: four decades of development of a topoisomerase II inhibitor; Eur. J. Cancer 34 1514
2) Smith et.al. (1994) Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells; Br. J. Cancer. 70 914

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Focus Biomolecules cell signaling reagent supplier, structure of Etoposide | Topoisomerase II inhibitor | CAS 33419-42-0

Catalog#  10-1123

$45.00
Quantity
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CAS:
33419-42-0
Catalog Number:
10-1123
Activity:
Topoisomerase II inhibitor
Chemical Name:
4_-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-_-D-glucopyranoside
Molecular Weight:
588.56
Molecular Formula:
C29H32O13
Solubility:
Soluble in DMSO (up to 30 mg/ml).
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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