FAAzo4 | Photoswitchable fatty acid
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $85.00 | ||
| 25 mg | $295.00 |
FAAzo4 (1882060-21-0) is a photoswitchable fatty acid that cells rapidly incorporate into membrane phosphatidylcholine (PC) and phosphatidylethanolamine(PE) residues, mainly in the endoplasmic reticulum (ER). These photoswitchable membrane fatty acids allow for photoisomerization (trans-cis) leading to changes in membrane viscosity. FAAzo4-treated cells displayed altered ER export for the proteins m-Cherry-TNFα and EGFP-GPI. An interesting new method for manipulating membrane biophysical properties in living cells.
References/Citations:
- Jimenez-Rojo et al. (2025), Optical Control of Membrane Viscosity Modulates ER-to-Golgi Trafficking; ACS Cent. Sci. 11 1736
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
FAAzo4 (1882060-21-0) is a photoswitchable fatty acid that cells rapidly incorporate into membrane phosphatidylcholine (PC) and phosphatidylethanolamine(PE) residues, mainly in the endoplasmic reticulum (ER). These photoswitchable membrane fatty acids allow for photoisomerization (trans-cis) leading to changes in membrane viscosity. FAAzo4-treated cells displayed altered ER export for the proteins m-Cherry-TNFα and EGFP-GPI. An interesting new method for manipulating membrane biophysical properties in living cells.
References/Citations:
- Jimenez-Rojo et al. (2025), Optical Control of Membrane Viscosity Modulates ER-to-Golgi Trafficking; ACS Cent. Sci. 11 1736
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