my account
Login
  Loading... Please wait...

Product Details

FK-866 HCl | NAD biosynthesis inhibitor

FK866 HCl (658084-64-1 base) is a nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis. FK-866 HCl extends lifespan of human cells. Cell permeable.

References/Citations

1) Hasmann et al. (2003), FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis;  Cancer Res., 63 7436 
2) Van der Veer et al. (2007), Extension of human cell lifespan by nicotinamide phosphoribosyltransferase;  J. Biol. Chem., 282 10841

swipe
FK-866 HC; | 658084-64-1 (free base) | Structure | Supplier

Catalog#  10-1109-0005

$90.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
658084-64-1 (base)
Catalog Number:
10-1109
Activity:
NAD biosynthesis inhibitor
Molecular Weight:
427.98
Molecular Formula:
C24H29N3O2 HCl
Solubility:
Soluble in Water (up to 40 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Material is hygroscopic, must be desiccated. Solutions in distilled water may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the FK-866 HCl | NAD biosynthesis inhibitor to your wish list.