Gabapentin | Neuropathic pain drug
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 25 mg | $55.00 | ||
| 100 mg | $200.00 |
Gabapentin (60142-96-3) is an approved drug for treatment of various types of neuropathic pain and some forms of epilepsy. The mechanism of action of gabapentin is not well understood. Despite being a structural mimic of GABA, it does not bind to GABA receptors at concentrations up to 1 mM.1,2 Some of its actions may be due to disrupting calcium channels.3
References/Citations:
1) Cheng et al. (2004), Does gabapentin act as an agonist at native GABA(B) receptors?; J. Biomed. Sci., 11 346
2) Lanneau et al. (2001), Gabapentin is not a GABAB receptor agonist; Neuropharmacology 41 965
3) Hendrich et al. (2008), Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin; Proc. Natl. Acad. Sci. USA, 105 3628
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Gabapentin (60142-96-3) is an approved drug for treatment of various types of neuropathic pain and some forms of epilepsy. The mechanism of action of gabapentin is not well understood. Despite being a structural mimic of GABA, it does not bind to GABA receptors at concentrations up to 1 mM.1,2 Some of its actions may be due to disrupting calcium channels.3
References/Citations:
1) Cheng et al. (2004), Does gabapentin act as an agonist at native GABA(B) receptors?; J. Biomed. Sci., 11 346
2) Lanneau et al. (2001), Gabapentin is not a GABAB receptor agonist; Neuropharmacology 41 965
3) Hendrich et al. (2008), Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin; Proc. Natl. Acad. Sci. USA, 105 3628
Related products
-
Rosiglitazone maleate | PPAR gamma agonist
From $55.00CAS:155141-29-0Catalog Number:10-1012Activity:PPARγ agonistAlternate Names:Avandia; BRL49653Chemical Name:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione maleateMolecular Weight:357.43Molecular Formula:C18H19N3O3SSolubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT -
Na Valproate | HDAC inhibitor
$40.00CAS:1069-66-5Catalog Number:10-1009Activity:HDAC inhibitorChemical Name:2-Propylpentanoic acid NaMolecular Weight:166.2Molecular Formula:C8H15O2·NaSolubility:Soluble in Water (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 monthsShipping Code:RT -
Phenylbutyrate Na | HDAC inhibitor
From $35.00CAS:1716-12-7Catalog Number:10-1118Activity:HDAC inhibitorAlternate Names:4-PB, PBNaChemical Name:4-Phenylbutyric acid sodium saltMolecular Weight:186.18Molecular Formula:C10H11NaO2Solubility:Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.