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Product Details

GW-441756 | NGFR kinase inhibitor

GW-441756 (504433-23-2) is a potent and selective TrkA kinase inhibitor (IC50 = 2 nM).

References/Citations
1) Wood et al. (2004) Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles. Bioorg. Med. Chem. Lett. 14 953
2) Takemoto et al. (2015) Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released froma strocytes in response to methylmercury; Environ. Toxicol. Pharmacol. 40 199 [Focus Citation]

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GW-441756 | 504433-23-2 | Structure | Supplier

Catalog#  10-1023

$135.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
504433-23-2
Catalog Number:
10-1023
Activity:
NGFR kinase inhibitor
Chemical Name:
1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
Molecular Weight:
275.31
Molecular Formula:
C17H13N3O
Solubility:
Soluble in DMSO (up to 5 mg/ml).
Physical Properties:
Orange solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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