HSL119 | HUNK inhibitor

HSL119 chemical structure

Available Options

Size:PriceQuantity 
10 mg$105.00
50 mg$375.00

HSL119 (2231745-56-3) is an inhibitor of the hormonally upregulated neu-associated kinase (HUNK); IC50 = 1.7 µM.  It inhibits several other kinases including ABL1, BRAF, FLT3, and RET.  HSL119 displays antitumor activity in several HER2/neu+ breast cancer models.

References/Citations:

  1. Dilday et al. (2024), Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer; Cell. Chem. Biol. 31 989
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Product Data Sheet:

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