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Product Details

Hypericin | Protein kinase C inhibitor

Hypericin (548-04-9) is a natural product found in St. John's Wort (Hypericum perforatum). A multifunctional agent that has been reported to be antidepressive, antineoplastic, antitumor and antiviral. Inhibitory effects have been demonstrated on various enzyme including MAO, PKC, dopamine-β-hydroxylase, reverse transcriptase, telomerase and CYP.1 Hypericin can cause photosensitivity - as a result, it is being investigated as an agent in photodynamic therapy.2

References/Citations
1) Kubin et al., (2005) Hypericin - the facts about a controversial agent; Current Pharm. Des., 11 233
2) Theodossiou et al., (2009) The multifaceted photocytotoxic profile of hypericin; Mol. Pharmacol., 6 1775

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Catalog#  10-2077

$58.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
548-04-9
Catalog Number:
10-2077
Activity:
Protein kinase C inhibitor
Chemical Name:
1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Molecular Weight:
504.45
Molecular Formula:
C30H16O8
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
Brown solid
Purity:
>98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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