IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
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