IMP-1700 | Bacterial DNA repair inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $195.00 |
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
Related products
-
Monensin Na | Golgi transport inhibitor
From $45.00CAS:22373-78-0Catalog Number:10-2659Activity:Golgi transport inhibitorChemical Names:2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, sodium saltAlternate Name:NSC-343257Molecular Weight:692.86Molecular Formula:C36H61O11·NaSolubility:Soluble in DMSO (25 mg/ml with warming)Physical Properties:White solidPurity:90-95% TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Antibiotic A-23187 | Ca2+ ionophore
From $70.00CAS:52665-69-7Catalog Number:10-2284Activity:Ca2+ ionophoreAlternate Names:CalcimycinMolecular Weight:523.62Molecular Formula:C29H37N3O6Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:Off-white solidPurity:98%Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.Shipping Code:RT -
PK150 | Sorafenib analog with unique antibacterial properties
From $55.00CAS:2165324-62-7Catalog Number:10-3960Activity:Sorafenib analog with unique antibacterial propertiesChemical Name:1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)ureaMolecular Weight:394.68Molecular Formula:C15H8ClF5N2O3Solubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:White solidPurity:99% by HPLCNMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.