ITD-1 | TGFß Degrader

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5 mg$70.00
25 mg$280.00
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ITD-1 (1099644-42-4) is a selective inhibitor of TGFß signaling (IC50=0.85 µM).1 Induces proteasomal degradation of TGFß type II receptor. Induces cardiomyocyte differentiation in embryonic stem cells.1,2

References/Citations:

  1. Willems et al. (2012), Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells; Cell Stem Cell, 11 242
  2. McKinney and McDevitt (2013), Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis; Trends Biotechnol., 31 78
1099644-42-4, ITD-1, ITD-1 supplier, ITD1, TGFß degrader

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Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

ITD-1 (1099644-42-4) is a selective inhibitor of TGFß signaling (IC50=0.85 µM).1 Induces proteasomal degradation of TGFß type II receptor. Induces cardiomyocyte differentiation in embryonic stem cells.1,2

References/Citations:

  1. Willems et al. (2012), Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells; Cell Stem Cell, 11 242
  2. McKinney and McDevitt (2013), Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis; Trends Biotechnol., 31 78