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Product Details

JNK inhibitor IX | JNK inhibitor

JNK inhibitor IX (312917-14-9) inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38α and a panel of 30 other kinases.1 Induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.2

 

References/Citations

1) Angell et al. (2007), N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3; Med. Chem. Lett., 17 1296
2) Jang et al. (2014), Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells ; Biochem. Biophys. Res. Commun., 452 845

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Catalog#  10-1528-0010

$65.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
312917-14-9
Catalog Number:
10-1528
Activity:
JNK inhibitor
Chemical Name:
N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide
Alternate Names:
TCS JNK 5a
Molecular Weight:
332.42
Molecular Formula:
C20H16N2OS
Solubility:
Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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