Jun9-72-2 | SARS-CoV2 PLpro inhibitor

CAS:
2657659-42-0
Catalog Number:
10-4966
Activity:
SARS-CoV2 PL protease inhibitor
Chemical Names:
4-[[Methyl-[(1R)-1-naphthalen-1-ylethyl]amino]methyl]phenol
Molecular Weight:
291.39
Molecular Formula:
C20H21NO
Solubility:
Soluble in DMSO (>30 mg/ml)
Physical Properties:
White solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$75.00
25 mg$275.00

Jun9-72-2 (CAS 2657659-42-0) is potent inhibitor (IC50 = 670 nM) of SARS-CoV2 papain-like (PL) protease.  It showed potent antiviral activity in both Vero E6 (EC50 = 6.62 µM) and Caco2-hACE2 (EC50 = 7.90 µM) cell lines.

References/Citations:

  • Ma et al. (2021), Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay; ACS Cent. Sci., 7 1245
CAS:
2657659-42-0
Catalog Number:
10-4966
Activity:
SARS-CoV2 PL protease inhibitor
Chemical Names:
4-[[Methyl-[(1R)-1-naphthalen-1-ylethyl]amino]methyl]phenol
Molecular Weight:
291.39
Molecular Formula:
C20H21NO
Solubility:
Soluble in DMSO (>30 mg/ml)
Physical Properties:
White solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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