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Product Details

JX-401 | p38 alpha MAP kinase inhibitor

JX401 (349087-34-9) is a potent, cell-permeable inhibitor of p38α (IC50 = 32 nM). No inhibition of p38β was observed at 10 μM.

References/Citations
1) Friedmann et al. (2006), JX401,a p38α inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast; Mol. Pharmacol., 70 1395.

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Focus Biomolecules cell signaling reagent supplier, structure JX-401 | p38 alpha MAP kinase inhibitor | CAS 349087-34-9

Catalog#  10-1022

$110.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
349087-34-9
Catalog Number:
10-1022
Activity:
p38α MAP kinase inhibitor
Chemical Name:
1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
Molecular Weight:
355.49
Molecular Formula:
C,sub>21H25NO2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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