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K252B | Kinase inhibitor (pan-specific)

CAS:
99570-78-2
Catalog Number:
10-2081
Activity:
Kinase inhibitor (pan-specific)
Molecular Weight:
453.46
Molecular Formula:
C26H19N3O5
Solubility:
Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 1 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Shipping Code:
RT

K252B (99570-78-2) is a potent pan-specific protein kinase inhibitor: PKA (K= 20 nM), PKG (Ki = 100 nM)1 as well as other kinases. Cell impermeable.2

References/Citations:

1) Kase et al. (1987), K252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases; Biochem. Biophys. Res. Commun., 142 436
2) Makino et al. (2012), Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling; PLoS One, 7 e41049

K252B | Kinase inhibitor (pan-specific) is also available in the Cellular Metabolism Library.
CAS:
99570-78-2
Catalog Number:
10-2081
Activity:
Kinase inhibitor (pan-specific)
Molecular Weight:
453.46
Molecular Formula:
C26H19N3O5
Solubility:
Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 1 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

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