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Kartogenin | Induces chrondrocyte differentiation

Kartogenin (4727-31-5) promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Kartogenin displays chrondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis. Cell permeable.

References/Citations
1) Johnson et al. (2012), A stem cell-based approach to cartilage repair; Science, 336 717

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Focus Biomolecules supplier, chemical structure of Kartogenin | Induces chrondrocyte differentiation | CAS 4727-31-5

Catalog#  10-1372

$48.00
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CAS:
4727-31-5
Catalog Number:
10-1372
Activity:
Induces chrondrocyte differentiation
Chemical Name:
2-[(1,1'-Biphenyl)-4-ylcarbamoyl]benzoic acid
Molecular Weight:
317.35
Molecular Formula:
C20H15NO3
Solubility:
Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 14 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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