LB244 | STING antagonist
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $100.00 | ||
| 25 mg | $375.00 |
LB244 is a potent (EC50 = 800 nM THP1 cells) and irreversible STING antagonist with markedly enhanced proteome-wide selectivity compared to parent compound BB-Cl-amidine. Potently inhibits STING signaling in vitro in both mouse and human cells and in vivo when formulated in 20% DMSO.
References/Citations:
- Barasa et al. (2023), Development of LB244, an irreversible STING Antagonist; J. Am. Chem. Soc. 145 20273
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
LB244 is a potent (EC50 = 800 nM THP1 cells) and irreversible STING antagonist with markedly enhanced proteome-wide selectivity compared to parent compound BB-Cl-amidine. Potently inhibits STING signaling in vitro in both mouse and human cells and in vivo when formulated in 20% DMSO.
References/Citations:
- Barasa et al. (2023), Development of LB244, an irreversible STING Antagonist; J. Am. Chem. Soc. 145 20273
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass