LDC1267 | Inhibitor of TAM kinases
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $270.00 |
LDC1267 (1361030-48-9) is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
References/Citations:
- Paolino et al. (2014), The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells; Nature 507 508
C30H26F2N4O5
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
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LDC1267 (1361030-48-9) is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
References/Citations:
- Paolino et al. (2014), The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells; Nature 507 508
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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