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LY-171883 | Cys LT1 antagonist

LY-171883 (88107-10-2) is a selective and orally active leukotriene D4 (LTD4) antagonist (Ki = 0.63 μM).1 It is also an activator of peroxisome proliferator-activated receptors (PPAR's).2,3

References/Citations
1) Fleisch et al. (1985), LY171883, 1-less than 2-hydroxy-3-propyl-4-less than 4-(1H-tetrazol-5-yl)butoxy greater than phenyl greater than ethanone, an orally active leukotriene D4 antagonist; J. Pharmacol. Exp. Ther., 233 148
2) Foxworthy and Eacho (1991) Effect of the peroxisome proliferator LY171883 on triglyceride accumulation in rats fed a fat-free diet; Biochem .Pharmacol. 42 1487
3) Kliewer et al. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors; Proc. Natl. Acad. Sci .USA 91 7355

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Focus Biomolecules cell signaling reagent supplier, chemical structure LY-171883 | Cys LT1 antagonist | CAS 88107-10-2

Catalog#  10-1052

$60.00
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CAS:
88107-10-2
Catalog Number:
10-1052
Activity:
Cys LT1 antagonist
Chemical Name:
1-[2-Hydroxy-3-propyl-4-[4-1H-tetrazol-5-yl)butoxy]phenyl]ethanone
Molecular Weight:
318.37
Molecular Formula:
C16H22N4O3
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml),
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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