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M-1 | Enhances mitochondrial fusion

Enhances mitochondrial fusion without interfering with endoplasmic reticulum (ER) and lysosome morphology.1 M-1 protects cells from mitochondrial fragmentation-associated cell death.2 Promotion of mitochondrial fusion has protective effects in rotenone-induced neurotoxicity.3 Cell permeable.

References/Citations

1) Andreaux et al. (2013), Pharmacological approaches to restore mitochondrial function; Nature Rev. Drug Disc., 12 465
2) Yang et al. (2015), Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA; Cell Mol. Life Sci., 72 2585
3) Peng et al. (2017), The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1a Regulates Rotenone-Induced Dopaminergic Neurotoxicity; Mol. Neurobiol., 54 3783

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M-1 | 219315-22-7 | Structure | Supplier

Catalog#  10-1598-0005

$48.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
219315-22-7
Catalog Number:
10-1598
Activity:
Enhances mitochondrial fusion
Chemical Name:
(E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol
Alternate Names:
1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
Molecular Weight:
364.05
Molecular Formula:
C14H10Cl4N2O
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 6 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 month.s
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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